Make layout responsive with bokeh

Hello guys, how are you?

Could someone guide me how to create a responsive layout similar to the image?

I trying with it, but dont works.

title=(row(logo,label))
layout= gridplot([[row],[column(P1,row(P5,P6)),column(P2,P3,P4)]],sizing_mode=‘stretch_both’)

doc.add_root(layout)