I observe a weird bug after upgrading to chrome 51 (sic), reproducible with https://bokeh.pydata.org/en/latest/docs/gallery/slider.html.
Dragging the 'Amplitude' handle works as expected but dragging 'Frequency' afterwards moves *both* of them together. Happens with 'Phase' and 'Offset' as well. Does not happen when I click on the base left or right of the .handle. You can even click anywhere in the .widget-box below the sliders to move them. It looks like chrome associates .bk-noUi-handle elements with the .bk-widget-box instead of their individual .bk-widget but only after they've been selected once.